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Diversity in the pre-immune immunoglobulin repertoire of SHR lines susceptible and resistant to end organ injury
We used next-generation sequencing to identify IGH genetic variation in two closely related hypertensive rat lines that differ in susceptibility to end-organ disease (SHR-A3 and SHR-B2). The two SHR lines differ extensively at the IGH locus from the rat reference genome sequence (RRGS) and from each...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257902/ https://www.ncbi.nlm.nih.gov/pubmed/25056448 http://dx.doi.org/10.1038/gene.2014.40 |