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The brown fat-enriched secreted factor Nrg4 preserves metabolic homeostasis through attenuating hepatic lipogenesis
Brown fat activates uncoupled respiration to defend against cold and contributes to systemic metabolic homeostasis. To date, the metabolic action of brown fat has been primarily attributed to its role in fuel oxidation and uncoupling protein 1 (UCP1)-mediated thermogenesis. Whether brown fat engages...
Autores principales: | Wang, Guo-Xiao, Zhao, Xu-Yun, Meng, Zhuo-Xian, Kern, Matthias, Dietrich, Arne, Chen, Zhimin, Cozacov, Zoharit, Zhou, Dequan, Okunade, Adewole L., Su, Xiong, Li, Siming, Blüher, Matthias, Lin, Jiandie D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257907/ https://www.ncbi.nlm.nih.gov/pubmed/25401691 http://dx.doi.org/10.1038/nm.3713 |
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