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Dynamic range of GSK3α not GSK3β is essential for bidirectional synaptic plasticity at hippocampal CA3-CA1 synapses
Glycogen synthase kinase-3 (GSK3), particularly the isoform GSK3β, has been implicated in a wide range of physiological systems and neurological disorders including Alzheimer's Disease. However, the functional importance of GSK3α has been largely untested. The multifunctionality of GSK3 limits...
Autores principales: | Shahab, Lion, Plattner, Florian, Irvine, Elaine E, Cummings, Damian M, Edwards, Frances A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258099/ https://www.ncbi.nlm.nih.gov/pubmed/25208523 http://dx.doi.org/10.1002/hipo.22362 |
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