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BamBam: genome sequence analysis tools for biologists
BACKGROUND: Massive computational power is needed to analyze the genomic data produced by next-generation sequencing, but extensive computational experience and specific knowledge of algorithms should not be necessary to run genomic analyses or interpret their results. FINDINGS: We present BamBam, a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258253/ https://www.ncbi.nlm.nih.gov/pubmed/25421351 http://dx.doi.org/10.1186/1756-0500-7-829 |
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author | Page, Justin T Liechty, Zachary S Huynh, Mark D Udall, Joshua A |
author_facet | Page, Justin T Liechty, Zachary S Huynh, Mark D Udall, Joshua A |
author_sort | Page, Justin T |
collection | PubMed |
description | BACKGROUND: Massive computational power is needed to analyze the genomic data produced by next-generation sequencing, but extensive computational experience and specific knowledge of algorithms should not be necessary to run genomic analyses or interpret their results. FINDINGS: We present BamBam, a package of tools for genome sequence analysis. BamBam contains tools that facilitate summarizing data from BAM alignment files and identifying features such as SNPs, indels, and haplotypes represented in those alignments. CONCLUSIONS: BamBam provides a powerful and convenient framework to analyze genome sequence data contained in BAM files. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/1756-0500-7-829) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-4258253 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-42582532014-12-08 BamBam: genome sequence analysis tools for biologists Page, Justin T Liechty, Zachary S Huynh, Mark D Udall, Joshua A BMC Res Notes Technical Note BACKGROUND: Massive computational power is needed to analyze the genomic data produced by next-generation sequencing, but extensive computational experience and specific knowledge of algorithms should not be necessary to run genomic analyses or interpret their results. FINDINGS: We present BamBam, a package of tools for genome sequence analysis. BamBam contains tools that facilitate summarizing data from BAM alignment files and identifying features such as SNPs, indels, and haplotypes represented in those alignments. CONCLUSIONS: BamBam provides a powerful and convenient framework to analyze genome sequence data contained in BAM files. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/1756-0500-7-829) contains supplementary material, which is available to authorized users. BioMed Central 2014-11-24 /pmc/articles/PMC4258253/ /pubmed/25421351 http://dx.doi.org/10.1186/1756-0500-7-829 Text en © Page et al.; licensee BioMed Central Ltd. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Technical Note Page, Justin T Liechty, Zachary S Huynh, Mark D Udall, Joshua A BamBam: genome sequence analysis tools for biologists |
title | BamBam: genome sequence analysis tools for biologists |
title_full | BamBam: genome sequence analysis tools for biologists |
title_fullStr | BamBam: genome sequence analysis tools for biologists |
title_full_unstemmed | BamBam: genome sequence analysis tools for biologists |
title_short | BamBam: genome sequence analysis tools for biologists |
title_sort | bambam: genome sequence analysis tools for biologists |
topic | Technical Note |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258253/ https://www.ncbi.nlm.nih.gov/pubmed/25421351 http://dx.doi.org/10.1186/1756-0500-7-829 |
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