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Combination of Peptide YY(3–36) with GLP-1(7–36 amide) Causes an Increase in First-Phase Insulin Secretion after IV Glucose

CONTEXT: The combination of peptide YY (PYY) and glucagon-like peptide-1 (GLP-1) has been proposed as a potential treatment for diabetes and obesity. However, the combined effects of these hormones, PYY(3–36) and GLP-1(7–36 amide), on glucose homeostasis are unknown. OBJECTIVE: This study sought to...

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Detalles Bibliográficos
Autores principales: Tan, Tricia M., Salem, Victoria, Troke, Rachel C., Alsafi, Ali, Field, Benjamin C. T., De Silva, Akila, Misra, Shivani, Baynes, Kevin C. R., Donaldson, Mandy, Minnion, James, Ghatei, Mohammad A., Godsland, Ian F., Bloom, Stephen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258604/
https://www.ncbi.nlm.nih.gov/pubmed/25144632
http://dx.doi.org/10.1210/jc.2014-2143