Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties

Hedgehog (Hh) is a secreted morphogen that elicits differentiation and patterning in developing tissues. Multiple proposed mechanisms to regulate Hh dispersion includes lipoprotein particles and exosomes. Here we report that vertebrate Sonic Hedgehog (Shh) is secreted on two types of extracellular-v...

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Detalles Bibliográficos
Autores principales: Vyas, Neha, Walvekar, Ankita, Tate, Dhananjay, Lakshmanan, Vairavan, Bansal, Dhiru, Cicero, Alessandra Lo, Raposo, Graca, Palakodeti, Dasaradhi, Dhawan, Jyotsna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258658/
https://www.ncbi.nlm.nih.gov/pubmed/25483805
http://dx.doi.org/10.1038/srep07357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258658/
https://www.ncbi.nlm.nih.gov/pubmed/25483805
http://dx.doi.org/10.1038/srep07357

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