Cargando…

Dose verification in carcinoma of uterine cervix patients undergoing 3D conformal radiotherapy with Farmer type ion chamber

External beam radiotherapy (EBRT) for carcinoma of uterine cervix is a basic line of treatment with three dimensional conformal radiotherapy (3DCRT) in large number of patients. There is need for an established method for verification dosimetry. We tried to document absorbed doses in a group of carc...

Descripción completa

Detalles Bibliográficos
Autores principales: Srinivas, Challapalli, Kumar, P Suman, Ravichandran, Ramamoorthy, Banerjee, S, Saxena, P.U, Kumar, E.S Arun, Pai, Dinesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258733/
https://www.ncbi.nlm.nih.gov/pubmed/25525313
http://dx.doi.org/10.4103/0971-6203.144492
_version_ 1782347916454658048
author Srinivas, Challapalli
Kumar, P Suman
Ravichandran, Ramamoorthy
Banerjee, S
Saxena, P.U
Kumar, E.S Arun
Pai, Dinesh K.
author_facet Srinivas, Challapalli
Kumar, P Suman
Ravichandran, Ramamoorthy
Banerjee, S
Saxena, P.U
Kumar, E.S Arun
Pai, Dinesh K.
author_sort Srinivas, Challapalli
collection PubMed
description External beam radiotherapy (EBRT) for carcinoma of uterine cervix is a basic line of treatment with three dimensional conformal radiotherapy (3DCRT) in large number of patients. There is need for an established method for verification dosimetry. We tried to document absorbed doses in a group of carcinoma cervix patients by inserting a 0.6 cc Farmer type ion chamber in the vaginal cavity. A special long perspex sleeve cap is designed to cover the chamber for using in the patient's body. Response of ionization chamber is checked earlier in water phantom with and without cap. Treatment planning was carried out with X-ray computed tomography (CT) scan and with the chamber along with cap in inserted position, and with the images Xio treatment planning system. Three measurements on 3 days at 5-6 fraction intervals were recorded in 12 patients. Electrometer measured charges are converted to absorbed dose at the chamber center, in vivo. Our results show good agreement with planned dose within 3% against prescribed dose. This study, is a refinement over our previous studies with transmission dosimetry and chemicals in ampules. This preliminary work shows promise that this can be followed as a routine dose check with special relevance to new protocols in the treatment of carcinoma cervix with EBRT.
format Online
Article
Text
id pubmed-4258733
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-42587332014-12-18 Dose verification in carcinoma of uterine cervix patients undergoing 3D conformal radiotherapy with Farmer type ion chamber Srinivas, Challapalli Kumar, P Suman Ravichandran, Ramamoorthy Banerjee, S Saxena, P.U Kumar, E.S Arun Pai, Dinesh K. J Med Phys Technical Note External beam radiotherapy (EBRT) for carcinoma of uterine cervix is a basic line of treatment with three dimensional conformal radiotherapy (3DCRT) in large number of patients. There is need for an established method for verification dosimetry. We tried to document absorbed doses in a group of carcinoma cervix patients by inserting a 0.6 cc Farmer type ion chamber in the vaginal cavity. A special long perspex sleeve cap is designed to cover the chamber for using in the patient's body. Response of ionization chamber is checked earlier in water phantom with and without cap. Treatment planning was carried out with X-ray computed tomography (CT) scan and with the chamber along with cap in inserted position, and with the images Xio treatment planning system. Three measurements on 3 days at 5-6 fraction intervals were recorded in 12 patients. Electrometer measured charges are converted to absorbed dose at the chamber center, in vivo. Our results show good agreement with planned dose within 3% against prescribed dose. This study, is a refinement over our previous studies with transmission dosimetry and chemicals in ampules. This preliminary work shows promise that this can be followed as a routine dose check with special relevance to new protocols in the treatment of carcinoma cervix with EBRT. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4258733/ /pubmed/25525313 http://dx.doi.org/10.4103/0971-6203.144492 Text en Copyright: © Journal of Medical Physics http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Technical Note
Srinivas, Challapalli
Kumar, P Suman
Ravichandran, Ramamoorthy
Banerjee, S
Saxena, P.U
Kumar, E.S Arun
Pai, Dinesh K.
Dose verification in carcinoma of uterine cervix patients undergoing 3D conformal radiotherapy with Farmer type ion chamber
title Dose verification in carcinoma of uterine cervix patients undergoing 3D conformal radiotherapy with Farmer type ion chamber
title_full Dose verification in carcinoma of uterine cervix patients undergoing 3D conformal radiotherapy with Farmer type ion chamber
title_fullStr Dose verification in carcinoma of uterine cervix patients undergoing 3D conformal radiotherapy with Farmer type ion chamber
title_full_unstemmed Dose verification in carcinoma of uterine cervix patients undergoing 3D conformal radiotherapy with Farmer type ion chamber
title_short Dose verification in carcinoma of uterine cervix patients undergoing 3D conformal radiotherapy with Farmer type ion chamber
title_sort dose verification in carcinoma of uterine cervix patients undergoing 3d conformal radiotherapy with farmer type ion chamber
topic Technical Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258733/
https://www.ncbi.nlm.nih.gov/pubmed/25525313
http://dx.doi.org/10.4103/0971-6203.144492
work_keys_str_mv AT srinivaschallapalli doseverificationincarcinomaofuterinecervixpatientsundergoing3dconformalradiotherapywithfarmertypeionchamber
AT kumarpsuman doseverificationincarcinomaofuterinecervixpatientsundergoing3dconformalradiotherapywithfarmertypeionchamber
AT ravichandranramamoorthy doseverificationincarcinomaofuterinecervixpatientsundergoing3dconformalradiotherapywithfarmertypeionchamber
AT banerjees doseverificationincarcinomaofuterinecervixpatientsundergoing3dconformalradiotherapywithfarmertypeionchamber
AT saxenapu doseverificationincarcinomaofuterinecervixpatientsundergoing3dconformalradiotherapywithfarmertypeionchamber
AT kumaresarun doseverificationincarcinomaofuterinecervixpatientsundergoing3dconformalradiotherapywithfarmertypeionchamber
AT paidineshk doseverificationincarcinomaofuterinecervixpatientsundergoing3dconformalradiotherapywithfarmertypeionchamber