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Modeling Time Resolved Light Propagation Inside a Realistic Human Head Model
Background: Near infrared spectroscopy imaging is one of the new techniques used for investigating structural and functionality of different body tissues. This is done by injecting light into the medium and measuring the photon intensity at the surface of the tissue. Methods: In this paper the diffe...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shiraz University of Medical Sciences
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258860/ https://www.ncbi.nlm.nih.gov/pubmed/25505770 |
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author | Bazrafkan, Sh Kazemi, K |
author_facet | Bazrafkan, Sh Kazemi, K |
author_sort | Bazrafkan, Sh |
collection | PubMed |
description | Background: Near infrared spectroscopy imaging is one of the new techniques used for investigating structural and functionality of different body tissues. This is done by injecting light into the medium and measuring the photon intensity at the surface of the tissue. Methods: In this paper the different medical applications, various imaging and simulation techniques of NIRS imaging is described. Each method is introduced and discussed. Then, the optimized model is prepared for numerical simulations. In this paper, the finite element method is used for solving the diffusion equation numerically. Results: Diffusion equation was solved for realistic human head model using finite element approach for a point light source and time resolved case. The photon intensity distribution in different head layers has been shown and the intensity orientation via the CSF layer has been illustrated. Conclusion: Simulating the photon transformation inside the tissue is essential for investigating the NIRS imaging technique. The finite element approach is a fast and accurate method for simulating this fact. The time resolved approach of this technique could illustrate the photon migration and intensity orientation in the tissue for time dependent light sources in tissues. |
format | Online Article Text |
id | pubmed-4258860 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Shiraz University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-42588602014-12-10 Modeling Time Resolved Light Propagation Inside a Realistic Human Head Model Bazrafkan, Sh Kazemi, K J Biomed Phys Eng Original Article Background: Near infrared spectroscopy imaging is one of the new techniques used for investigating structural and functionality of different body tissues. This is done by injecting light into the medium and measuring the photon intensity at the surface of the tissue. Methods: In this paper the different medical applications, various imaging and simulation techniques of NIRS imaging is described. Each method is introduced and discussed. Then, the optimized model is prepared for numerical simulations. In this paper, the finite element method is used for solving the diffusion equation numerically. Results: Diffusion equation was solved for realistic human head model using finite element approach for a point light source and time resolved case. The photon intensity distribution in different head layers has been shown and the intensity orientation via the CSF layer has been illustrated. Conclusion: Simulating the photon transformation inside the tissue is essential for investigating the NIRS imaging technique. The finite element approach is a fast and accurate method for simulating this fact. The time resolved approach of this technique could illustrate the photon migration and intensity orientation in the tissue for time dependent light sources in tissues. Shiraz University of Medical Sciences 2014-06-08 /pmc/articles/PMC4258860/ /pubmed/25505770 Text en © 2014: Journal of Biomedical Physics and Engineering This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported License (http://creativecommons.org/licenses/by-nc/3.0/deed.en_US), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Bazrafkan, Sh Kazemi, K Modeling Time Resolved Light Propagation Inside a Realistic Human Head Model |
title | Modeling Time Resolved Light Propagation Inside a Realistic Human Head Model |
title_full | Modeling Time Resolved Light Propagation Inside a Realistic Human Head Model |
title_fullStr | Modeling Time Resolved Light Propagation Inside a Realistic Human Head Model |
title_full_unstemmed | Modeling Time Resolved Light Propagation Inside a Realistic Human Head Model |
title_short | Modeling Time Resolved Light Propagation Inside a Realistic Human Head Model |
title_sort | modeling time resolved light propagation inside a realistic human head model |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258860/ https://www.ncbi.nlm.nih.gov/pubmed/25505770 |
work_keys_str_mv | AT bazrafkansh modelingtimeresolvedlightpropagationinsidearealistichumanheadmodel AT kazemik modelingtimeresolvedlightpropagationinsidearealistichumanheadmodel |