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Inhibition of STAT3-interacting protein 1 (STATIP1) promotes STAT3 transcriptional up-regulation and imatinib mesylate resistance in the chronic myeloid leukemia
BACKGROUND: Signal transducer and activator of transcription 3 (STAT3) is an important transcriptional factor frequently associated with the proliferation and survival of a large number of distinct cancer types. However, the signaling pathways and mechanisms that regulate STAT3 activation remain to...
Autores principales: | Mencalha, André L, Corrêa, Stephany, Salles, Daniela, Du Rocher, Bárbara, Santiago, Marcelo F, Abdelhay, Eliana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258947/ https://www.ncbi.nlm.nih.gov/pubmed/25417721 http://dx.doi.org/10.1186/1471-2407-14-866 |
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