Cargando…
Transduction of ferret airway epithelia using a pre-treatment and lentiviral gene vector
BACKGROUND: The safety and efficiency of gene therapies for cystic fibrosis (CF) need to be assessed in pre-clinical models. Using the normal ferret, this study sought to determine whether ferret airway epithelia could be transduced with a lysophosphatidylcholine (LPC) pre-treatment followed by a VS...
Autores principales: | Cmielewski, Patricia, Farrow, Nigel, Donnelley, Martin, McIntyre, Chantelle, Penny-Dimri, Jahan, Kuchel, Tim, Parsons, David |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258949/ https://www.ncbi.nlm.nih.gov/pubmed/25413892 http://dx.doi.org/10.1186/1471-2466-14-183 |
Ejemplares similares
-
Repeat or single-dose lentiviral vector administration to mouse lungs? It’s all about the timing
por: Donnelley, Martin, et al.
Publicado: (2023) -
Breaching the Delivery Barrier: Chemical and Physical Airway Epithelium Disruption Strategies for Enhancing Lentiviral-Mediated Gene Therapy
por: McCarron, Alexandra, et al.
Publicado: (2021) -
Airway gene transfer in a non-human primate: Lentiviral gene expression in marmoset lungs
por: Farrow, N., et al.
Publicado: (2013) -
Large-scale production of lentiviral vectors using multilayer cell factories
por: Rout-Pitt, Nathan, et al.
Publicado: (2018) -
Assessment of Lentiviral Vector Mediated CFTR Correction in Mice Using an Improved Rapid in vivo Nasal Potential Difference Measurement Protocol
por: Cmielewski, P., et al.
Publicado: (2021)