Mutational analysis of the tyrosine kinome in serous and clear cell endometrial cancer uncovers rare somatic mutations in TNK2 and DDR1

BACKGROUND: Endometrial cancer (EC) is the 8(th) leading cause of cancer death amongst American women. Most ECs are endometrioid, serous, or clear cell carcinomas, or an admixture of histologies. Serous and clear ECs are clinically aggressive tumors for which alternative therapeutic approaches are n...

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Detalles Bibliográficos
Autores principales: Rudd, Meghan L, Mohamed, Hassan, Price, Jessica C, O’Hara, Andrea J, Le Gallo, Matthieu, Urick, Mary Ellen, Cruz, Pedro, Zhang, Suiyuan, Hansen, Nancy F, Godwin, Andrew K, Sgroi, Dennis C, Wolfsberg, Tyra G, Mullikin, James C, Merino, Maria J, Bell, Daphne W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258955/
https://www.ncbi.nlm.nih.gov/pubmed/25427824
http://dx.doi.org/10.1186/1471-2407-14-884

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