Paraganglioma and pheochromocytoma upon maternal transmission of SDHD mutations

BACKGROUND: The SDHD gene encodes a subunit of the mitochondrial tricarboxylic acid cycle enzyme and tumor suppressor, succinate dehydrogenase. Mutations in this gene show a remarkable pattern of parent-of-origin related tumorigenesis, with almost all SDHD-related cases of head and neck paragangliom...

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Detalles Bibliográficos
Autores principales: Bayley, Jean-Pierre, Oldenburg, Rogier A, Nuk, Jennifer, Hoekstra, Attje S, van der Meer, Conny A, Korpershoek, Esther, McGillivray, Barbara, Corssmit, Eleonora PM, Dinjens, Winand NM, de Krijger, Ronald R, Devilee, Peter, Jansen, Jeroen C, Hes, Frederik J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259087/
https://www.ncbi.nlm.nih.gov/pubmed/25300370
http://dx.doi.org/10.1186/s12881-014-0111-8

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