Phosphorylation of Ribosomal Protein S6 Kinase 1 at Thr421/Ser424 and Dephosphorylation at Thr389 Regulates SP600125-Induced Polyploidization of Megakaryocytic Cell Lines

Megakaryocytes (MKs) are one of the few cell types that become polyploid; however, the mechanisms by which these cells are designated to become polyploid are not fully understood. In this investigation, we successfully established two relatively synchronous polyploid cell models by inducing Dami and...

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Detalles Bibliográficos
Autores principales: Li, Chang-Ling, Yang, Jin-Gang, Lin, Di, Zhao, Yong-Shan, Liu, Shuo, Xing, Si-Ning, Zhao, Song, Chen, Cong-Qin, Jiang, Zhi-Ming, Pu, Fei-Fei, Cao, Jian-Ping, Ma, Dong-Chu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259319/
https://www.ncbi.nlm.nih.gov/pubmed/25486532
http://dx.doi.org/10.1371/journal.pone.0114389

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