Exposure to Mitochondrial Genotoxins and Dopaminergic Neurodegeneration in Caenorhabditis elegans

Neurodegeneration has been correlated with mitochondrial DNA (mtDNA) damage and exposure to environmental toxins, but causation is unclear. We investigated the ability of several known environmental genotoxins and neurotoxins to cause mtDNA damage, mtDNA depletion, and neurodegeneration in Caenorhab...

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Detalles Bibliográficos
Autores principales: González-Hunt, Claudia P., Leung, Maxwell C. K., Bodhicharla, Rakesh K., McKeever, Madeline G., Arrant, Andrew E., Margillo, Kathleen M., Ryde, Ian T., Cyr, Derek D., Kosmaczewski, Sara G., Hammarlund, Marc, Meyer, Joel N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259338/
https://www.ncbi.nlm.nih.gov/pubmed/25486066
http://dx.doi.org/10.1371/journal.pone.0114459

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