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The Molecular Signature of the Stroma Response in Prostate Cancer-Induced Osteoblastic Bone Metastasis Highlights Expansion of Hematopoietic and Prostate Epithelial Stem Cell Niches

The reciprocal interaction between cancer cells and the tissue-specific stroma is critical for primary and metastatic tumor growth progression. Prostate cancer cells colonize preferentially bone (osteotropism), where they alter the physiological balance between osteoblast-mediated bone formation and...

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Detalles Bibliográficos
Autores principales:	Özdemir, Berna C., Hensel, Janine, Secondini, Chiara, Wetterwald, Antoinette, Schwaninger, Ruth, Fleischmann, Achim, Raffelsberger, Wolfgang, Poch, Olivier, Delorenzi, Mauro, Temanni, Ramzi, Mills, Ian G., van der Pluijm, Gabri, Thalmann, George N., Cecchini, Marco G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259356/ https://www.ncbi.nlm.nih.gov/pubmed/25485970 http://dx.doi.org/10.1371/journal.pone.0114530

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