Comparative trial between the use of amoxicillin and amoxicillin clavulanate in the removal of third molars
Objectives: The purpose of this study was to compare the use of amoxicillin (1g) vs amoxicillin and clavulanate (875/125mg) after extraction of retained third molars for prevention of infectious complications. Study Design: The study involved 546 patients attending for removal a retained third molar...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medicina Oral S.L.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259379/ https://www.ncbi.nlm.nih.gov/pubmed/24880449 http://dx.doi.org/10.4317/medoral.19778 |
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author | Iglesias-Martín, Fernando García-Perla-García, Alberto Yañez-Vico, Rosa Rosa, Elena Arjona-Gerveno, Esther González-Padilla, Juan D. Gutierrez-Pérez, Jose L. Torres-Lagares, Daniel |
author_facet | Iglesias-Martín, Fernando García-Perla-García, Alberto Yañez-Vico, Rosa Rosa, Elena Arjona-Gerveno, Esther González-Padilla, Juan D. Gutierrez-Pérez, Jose L. Torres-Lagares, Daniel |
author_sort | Iglesias-Martín, Fernando |
collection | PubMed |
description | Objectives: The purpose of this study was to compare the use of amoxicillin (1g) vs amoxicillin and clavulanate (875/125mg) after extraction of retained third molars for prevention of infectious complications. Study Design: The study involved 546 patients attending for removal a retained third molar and divided in to two groups: Group 1 - amoxicillin and clavunate (875/125mg) group (n=257) and Group 2 - amoxicillin (1g) group (n=289). All patients were recalled for investigating the possibility of infection, presence of diarrhea and further analgesic intake. Results: From a total of 546 patients, the frequency of infection was 1.4%, without no statistically differences between the two groups. Group 1 showed statistically higher presence of patients with gastrointestinal complications (p>0.05). In 546 patients, 2.7% of patients reported severe pain that would not relieve with medication. Conclusions: The results of our study show that the use of amoxicillin (1g) and amoxicillin and clavunate (875/125mg) is similar efficacious in preventing infection after retained third molar extraction but amoxicillin and clavunate (875/125mg) produces more gastrointestinal discomfort. Key words:Amoxicillin, clavulanate, third molars, complications. |
format | Online Article Text |
id | pubmed-4259379 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Medicina Oral S.L. |
record_format | MEDLINE/PubMed |
spelling | pubmed-42593792014-12-10 Comparative trial between the use of amoxicillin and amoxicillin clavulanate in the removal of third molars Iglesias-Martín, Fernando García-Perla-García, Alberto Yañez-Vico, Rosa Rosa, Elena Arjona-Gerveno, Esther González-Padilla, Juan D. Gutierrez-Pérez, Jose L. Torres-Lagares, Daniel Med Oral Patol Oral Cir Bucal Research Objectives: The purpose of this study was to compare the use of amoxicillin (1g) vs amoxicillin and clavulanate (875/125mg) after extraction of retained third molars for prevention of infectious complications. Study Design: The study involved 546 patients attending for removal a retained third molar and divided in to two groups: Group 1 - amoxicillin and clavunate (875/125mg) group (n=257) and Group 2 - amoxicillin (1g) group (n=289). All patients were recalled for investigating the possibility of infection, presence of diarrhea and further analgesic intake. Results: From a total of 546 patients, the frequency of infection was 1.4%, without no statistically differences between the two groups. Group 1 showed statistically higher presence of patients with gastrointestinal complications (p>0.05). In 546 patients, 2.7% of patients reported severe pain that would not relieve with medication. Conclusions: The results of our study show that the use of amoxicillin (1g) and amoxicillin and clavunate (875/125mg) is similar efficacious in preventing infection after retained third molar extraction but amoxicillin and clavunate (875/125mg) produces more gastrointestinal discomfort. Key words:Amoxicillin, clavulanate, third molars, complications. Medicina Oral S.L. 2014-11 2014-06-01 /pmc/articles/PMC4259379/ /pubmed/24880449 http://dx.doi.org/10.4317/medoral.19778 Text en Copyright: © 2014 Medicina Oral S.L. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Iglesias-Martín, Fernando García-Perla-García, Alberto Yañez-Vico, Rosa Rosa, Elena Arjona-Gerveno, Esther González-Padilla, Juan D. Gutierrez-Pérez, Jose L. Torres-Lagares, Daniel Comparative trial between the use of amoxicillin and amoxicillin clavulanate in the removal of third molars |
title | Comparative trial between the use of amoxicillin and amoxicillin
clavulanate in the removal of third molars |
title_full | Comparative trial between the use of amoxicillin and amoxicillin
clavulanate in the removal of third molars |
title_fullStr | Comparative trial between the use of amoxicillin and amoxicillin
clavulanate in the removal of third molars |
title_full_unstemmed | Comparative trial between the use of amoxicillin and amoxicillin
clavulanate in the removal of third molars |
title_short | Comparative trial between the use of amoxicillin and amoxicillin
clavulanate in the removal of third molars |
title_sort | comparative trial between the use of amoxicillin and amoxicillin
clavulanate in the removal of third molars |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259379/ https://www.ncbi.nlm.nih.gov/pubmed/24880449 http://dx.doi.org/10.4317/medoral.19778 |
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