Comparative trial between the use of amoxicillin and amoxicillin clavulanate in the removal of third molars

Objectives: The purpose of this study was to compare the use of amoxicillin (1g) vs amoxicillin and clavulanate (875/125mg) after extraction of retained third molars for prevention of infectious complications. Study Design: The study involved 546 patients attending for removal a retained third molar...

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Autores principales: Iglesias-Martín, Fernando, García-Perla-García, Alberto, Yañez-Vico, Rosa, Rosa, Elena, Arjona-Gerveno, Esther, González-Padilla, Juan D., Gutierrez-Pérez, Jose L., Torres-Lagares, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medicina Oral S.L. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259379/
https://www.ncbi.nlm.nih.gov/pubmed/24880449
http://dx.doi.org/10.4317/medoral.19778
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author Iglesias-Martín, Fernando
García-Perla-García, Alberto
Yañez-Vico, Rosa
Rosa, Elena
Arjona-Gerveno, Esther
González-Padilla, Juan D.
Gutierrez-Pérez, Jose L.
Torres-Lagares, Daniel
author_facet Iglesias-Martín, Fernando
García-Perla-García, Alberto
Yañez-Vico, Rosa
Rosa, Elena
Arjona-Gerveno, Esther
González-Padilla, Juan D.
Gutierrez-Pérez, Jose L.
Torres-Lagares, Daniel
author_sort Iglesias-Martín, Fernando
collection PubMed
description Objectives: The purpose of this study was to compare the use of amoxicillin (1g) vs amoxicillin and clavulanate (875/125mg) after extraction of retained third molars for prevention of infectious complications. Study Design: The study involved 546 patients attending for removal a retained third molar and divided in to two groups: Group 1 - amoxicillin and clavunate (875/125mg) group (n=257) and Group 2 - amoxicillin (1g) group (n=289). All patients were recalled for investigating the possibility of infection, presence of diarrhea and further analgesic intake. Results: From a total of 546 patients, the frequency of infection was 1.4%, without no statistically differences between the two groups. Group 1 showed statistically higher presence of patients with gastrointestinal complications (p>0.05). In 546 patients, 2.7% of patients reported severe pain that would not relieve with medication. Conclusions: The results of our study show that the use of amoxicillin (1g) and amoxicillin and clavunate (875/125mg) is similar efficacious in preventing infection after retained third molar extraction but amoxicillin and clavunate (875/125mg) produces more gastrointestinal discomfort. Key words:Amoxicillin, clavulanate, third molars, complications.
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spelling pubmed-42593792014-12-10 Comparative trial between the use of amoxicillin and amoxicillin clavulanate in the removal of third molars Iglesias-Martín, Fernando García-Perla-García, Alberto Yañez-Vico, Rosa Rosa, Elena Arjona-Gerveno, Esther González-Padilla, Juan D. Gutierrez-Pérez, Jose L. Torres-Lagares, Daniel Med Oral Patol Oral Cir Bucal Research Objectives: The purpose of this study was to compare the use of amoxicillin (1g) vs amoxicillin and clavulanate (875/125mg) after extraction of retained third molars for prevention of infectious complications. Study Design: The study involved 546 patients attending for removal a retained third molar and divided in to two groups: Group 1 - amoxicillin and clavunate (875/125mg) group (n=257) and Group 2 - amoxicillin (1g) group (n=289). All patients were recalled for investigating the possibility of infection, presence of diarrhea and further analgesic intake. Results: From a total of 546 patients, the frequency of infection was 1.4%, without no statistically differences between the two groups. Group 1 showed statistically higher presence of patients with gastrointestinal complications (p>0.05). In 546 patients, 2.7% of patients reported severe pain that would not relieve with medication. Conclusions: The results of our study show that the use of amoxicillin (1g) and amoxicillin and clavunate (875/125mg) is similar efficacious in preventing infection after retained third molar extraction but amoxicillin and clavunate (875/125mg) produces more gastrointestinal discomfort. Key words:Amoxicillin, clavulanate, third molars, complications. Medicina Oral S.L. 2014-11 2014-06-01 /pmc/articles/PMC4259379/ /pubmed/24880449 http://dx.doi.org/10.4317/medoral.19778 Text en Copyright: © 2014 Medicina Oral S.L. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Iglesias-Martín, Fernando
García-Perla-García, Alberto
Yañez-Vico, Rosa
Rosa, Elena
Arjona-Gerveno, Esther
González-Padilla, Juan D.
Gutierrez-Pérez, Jose L.
Torres-Lagares, Daniel
Comparative trial between the use of amoxicillin and amoxicillin clavulanate in the removal of third molars
title Comparative trial between the use of amoxicillin and amoxicillin clavulanate in the removal of third molars
title_full Comparative trial between the use of amoxicillin and amoxicillin clavulanate in the removal of third molars
title_fullStr Comparative trial between the use of amoxicillin and amoxicillin clavulanate in the removal of third molars
title_full_unstemmed Comparative trial between the use of amoxicillin and amoxicillin clavulanate in the removal of third molars
title_short Comparative trial between the use of amoxicillin and amoxicillin clavulanate in the removal of third molars
title_sort comparative trial between the use of amoxicillin and amoxicillin clavulanate in the removal of third molars
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259379/
https://www.ncbi.nlm.nih.gov/pubmed/24880449
http://dx.doi.org/10.4317/medoral.19778
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