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How mRNA is misspliced in acute myelogenous leukemia (AML)?

Approximately one-third of expressed genes are misspliced in AML, opening the possibility that additional factors than splicing factor mutations might cause RNA missplicing in these diseases. AML cells harbor a constellation of epigenetic modifications and regularly express large amounts of WT1 tran...

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Detalles Bibliográficos
Autores principales:	Mohamed, Aminetou Mint, Thénoz, Morgan, Solly, Françoise, Balsat, Marie, Mortreux, Franck, Wattel, Eric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259418/ https://www.ncbi.nlm.nih.gov/pubmed/25375204

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