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AXL kinase as a novel target for cancer therapy

The AXL receptor tyrosine kinase and its major ligand, GAS6 have been demonstrated to be overexpressed and activated in many human cancers (such as lung, breast, and pancreatic cancer) and have been correlated with poor prognosis, promotion of increased invasiveness/metastasis, the EMT phenotype and...

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Detalles Bibliográficos
Autores principales: Wu, Xiaoliang, Liu, Xuewen, Koul, Sanjay, Lee, Chang Youl, Zhang, Zhenfeng, Halmos, Balazs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259419/
https://www.ncbi.nlm.nih.gov/pubmed/25337673