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Targeting L1 cell adhesion molecule expression using liposome-encapsulated siRNA suppresses prostate cancer bone metastasis and growth
The L1 cell adhesion molecule (L1CAM) has been implicated in tumor progression of many types of cancers, but its role in prostate cancer and its application in targeted gene therapy have not been investigated. Herein, we demonstrated that the L1CAM was expressed in androgen-insensitive and highly me...
Autores principales: | Sung, Shian-Ying, Wu, I-Hui, Chuang, Pei-Hsin, Petros, John A., Wu, Hsi-Chin, Zeng, Hong-Jie, Huang, Wei-Chien, Chung, Leland W. K., Hsieh, Chia-Ling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259447/ https://www.ncbi.nlm.nih.gov/pubmed/25294816 |
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