PKM2 phosphorylates MLC2 and regulates cytokinesis of tumor cells

Pyruvate kinase M2 (PKM2) is expressed at high levels during embryonic development and tumor progression and is important for cell growth. However, it is not known whether it directly controls cell division. Here, we found that Aurora B phosphorylates PKM2, but not PKM1, at T45; this phosphorylation...

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Detalles Bibliográficos
Autores principales: Jiang, Yuhui, Wang, Yugang, Wang, Ting, Hawke, David H., Zheng, Yanhua, Li, Xinjian, Zhou, Qin, Majumder, Sadhan, Bi, Erfei, Liu, David X., Huang, Suyun, Lu, Zhimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259466/
https://www.ncbi.nlm.nih.gov/pubmed/25412762
http://dx.doi.org/10.1038/ncomms6566

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259466/
https://www.ncbi.nlm.nih.gov/pubmed/25412762
http://dx.doi.org/10.1038/ncomms6566

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