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Behavioral Phenotyping of Parkin-Deficient Mice: Looking for Early Preclinical Features of Parkinson's Disease

There is considerable evidence showing that the neurodegenerative processes that lead to sporadic Parkinson's disease (PD) begin many years before the appearance of the characteristic motor symptoms. Neuropsychiatric, sensorial and cognitive deficits are recognized as early non-motor manifestat...

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Detalles Bibliográficos
Autores principales: Rial, Daniel, Castro, Adalberto A., Machado, Nuno, Garção, Pedro, Gonçalves, Francisco Q., Silva, Henrique B., Tomé, Ângelo R., Köfalvi, Attila, Corti, Olga, Raisman-Vozari, Rita, Cunha, Rodrigo A., Prediger, Rui D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259468/
https://www.ncbi.nlm.nih.gov/pubmed/25486126
http://dx.doi.org/10.1371/journal.pone.0114216

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