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Behavioral Phenotyping of Parkin-Deficient Mice: Looking for Early Preclinical Features of Parkinson's Disease
There is considerable evidence showing that the neurodegenerative processes that lead to sporadic Parkinson's disease (PD) begin many years before the appearance of the characteristic motor symptoms. Neuropsychiatric, sensorial and cognitive deficits are recognized as early non-motor manifestat...
Autores principales: | Rial, Daniel, Castro, Adalberto A., Machado, Nuno, Garção, Pedro, Gonçalves, Francisco Q., Silva, Henrique B., Tomé, Ângelo R., Köfalvi, Attila, Corti, Olga, Raisman-Vozari, Rita, Cunha, Rodrigo A., Prediger, Rui D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259468/ https://www.ncbi.nlm.nih.gov/pubmed/25486126 http://dx.doi.org/10.1371/journal.pone.0114216 |
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