BRCA2 diffuses as oligomeric clusters with RAD51 and changes mobility after DNA damage in live cells

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Genome maintenance by homologous recombination depends on coordinating many proteins in time and space to assemble at DNA break sites. To understand this process, we followed the mobility of BRCA2, a critical recombination mediator, in live cells at the single-molecule level using both single-partic...

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Detalles Bibliográficos
Autores principales: Reuter, Marcel, Zelensky, Alex, Smal, Ihor, Meijering, Erik, van Cappellen, Wiggert A., de Gruiter, H. Martijn, van Belle, Gijsbert J., van Royen, Martin E., Houtsmuller, Adriaan B., Essers, Jeroen, Kanaar, Roland, Wyman, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259808/
https://www.ncbi.nlm.nih.gov/pubmed/25488918
http://dx.doi.org/10.1083/jcb.201405014

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