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BRCA2 diffuses as oligomeric clusters with RAD51 and changes mobility after DNA damage in live cells
Genome maintenance by homologous recombination depends on coordinating many proteins in time and space to assemble at DNA break sites. To understand this process, we followed the mobility of BRCA2, a critical recombination mediator, in live cells at the single-molecule level using both single-partic...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259808/ https://www.ncbi.nlm.nih.gov/pubmed/25488918 http://dx.doi.org/10.1083/jcb.201405014 |
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BRCA2 diffuses as oligomeric clusters with RAD51 and changes mobility after DNA damage in live cells
por Reuter, Marcel, Zelensky, Alex, Smal, Ihor, Meijering, Erik, van Cappellen, Wiggert A., de Gruiter, H. Martijn, van Belle, Gijsbert J., van Royen, Martin E., Houtsmuller, Adriaan B., Essers, Jeroen, Kanaar, Roland, Wyman, Claire
Publicado 2015
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Publicado 2015
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Online
Artículo
Texto