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CDK5 is a major regulator of the tumor suppressor DLC1
DLC1 is a tumor suppressor protein whose full activity depends on its presence at focal adhesions, its Rho–GTPase activating protein (Rho-GAP) function, and its ability to bind several ligands, including tensin and talin. However, the mechanisms that regulate and coordinate these activities remain p...
Autores principales: | Tripathi, Brajendra K., Qian, Xiaolan, Mertins, Philipp, Wang, Dunrui, Papageorge, Alex G., Carr, Steven A., Lowy, Douglas R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259810/ https://www.ncbi.nlm.nih.gov/pubmed/25452387 http://dx.doi.org/10.1083/jcb.201405105 |
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