Accumulation of abasic sites induces genomic instability in normal human gastric epithelial cells during Helicobacter pylori infection

Helicobacter pylori infection of the human stomach is associated with inflammation that leads to the release of reactive oxygen and nitrogen species (RONs), eliciting DNA damage in host cells. Unrepaired DNA damage leads to genomic instability that is associated with cancer. Base excision repair (BE...

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Detalles Bibliográficos
Autores principales: Kidane, D, Murphy, D L, Sweasy, J B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259965/
https://www.ncbi.nlm.nih.gov/pubmed/25417725
http://dx.doi.org/10.1038/oncsis.2014.42

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