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SERPINE1 and SMA expression at the invasive front predict extracapsular spread and survival in oral squamous cell carcinoma

BACKGROUND: Extracapsular spread (ECS) in cervical lymph nodes is the single-most prognostic clinical variable in oral squamous cell carcinoma (OSCC), but diagnosis is possible only after histopathological examination. A promising biomarker in the primary tumour, alpha smooth muscle actin (SMA) has...

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Detalles Bibliográficos
Autores principales: Dhanda, J, Triantafyllou, A, Liloglou, T, Kalirai, H, Lloyd, B, Hanlon, R, Shaw, R J, Sibson, D R, Risk, J M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260028/
https://www.ncbi.nlm.nih.gov/pubmed/25268377
http://dx.doi.org/10.1038/bjc.2014.500