Excess of miRNA-378a-5p perturbs mitotic fidelity and correlates with breast cancer tumourigenesis in vivo

BACKGROUND: Optimal expression and proper function of key mitotic proteins facilitate control and repair processes that aim to prevent loss or gain of chromosomes, a hallmark of cancer. Altered expression of small regulatory microRNAs is associated with tumourigenesis and metastasis but the impact o...

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Detalles Bibliográficos
Autores principales: Winsel, S, Mäki-Jouppila, J, Tambe, M, Aure, M R, Pruikkonen, S, Salmela, A-L, Halonen, T, Leivonen, S-K, Kallio, L, Børresen-Dale, A-L, Kallio, M J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260036/
https://www.ncbi.nlm.nih.gov/pubmed/25268374
http://dx.doi.org/10.1038/bjc.2014.524

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