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Prevention Strategies for Gastric Cancer: A Global Perspective
Despite the substantial burden of gastric cancer worldwide, population strategies for primary prevention have not been introduced in any country. Recognizing the causal role of Helicobacter pylori infection, there is increasing interest in population-based programs to eradicate the infection to prev...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Gastrointestinal Endoscopy
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260094/ https://www.ncbi.nlm.nih.gov/pubmed/25505712 http://dx.doi.org/10.5946/ce.2014.47.6.478 |
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author | Park, Jin Young von Karsa, Lawrence Herrero, Rolando |
author_facet | Park, Jin Young von Karsa, Lawrence Herrero, Rolando |
author_sort | Park, Jin Young |
collection | PubMed |
description | Despite the substantial burden of gastric cancer worldwide, population strategies for primary prevention have not been introduced in any country. Recognizing the causal role of Helicobacter pylori infection, there is increasing interest in population-based programs to eradicate the infection to prevent gastric cancer. Nonetheless, the paucity of available evidence on feasibility and effectiveness has prevented implementation of this approach. There are very few secondary prevention programs based on screening with endoscopy or radiography, notably in the Republic of Korea and Japan, two of the countries with the highest incidence rates of gastric cancer. In Korea, where the organized screening program is in place, survival rate of gastric cancer is as high as 67%. More research is needed to quantify the specific contribution of the screening program to observed declines in mortality rates. Gastric cancer screening is unlikely to be feasible in many Low-Middle Income Countries where the gastric cancer burden is high. Prevention strategies are still under development and the optimal approach may differ depending on local conditions and societal values. The present review gives an overview of the etiology and burden of the disease, and possible prevention strategies for countries and regions confronted with a significant burden of disease. |
format | Online Article Text |
id | pubmed-4260094 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | The Korean Society of Gastrointestinal Endoscopy |
record_format | MEDLINE/PubMed |
spelling | pubmed-42600942014-12-10 Prevention Strategies for Gastric Cancer: A Global Perspective Park, Jin Young von Karsa, Lawrence Herrero, Rolando Clin Endosc Focused Review Series: Endoscopic Screening and Surveillance for Gastrointestinal Cancer Despite the substantial burden of gastric cancer worldwide, population strategies for primary prevention have not been introduced in any country. Recognizing the causal role of Helicobacter pylori infection, there is increasing interest in population-based programs to eradicate the infection to prevent gastric cancer. Nonetheless, the paucity of available evidence on feasibility and effectiveness has prevented implementation of this approach. There are very few secondary prevention programs based on screening with endoscopy or radiography, notably in the Republic of Korea and Japan, two of the countries with the highest incidence rates of gastric cancer. In Korea, where the organized screening program is in place, survival rate of gastric cancer is as high as 67%. More research is needed to quantify the specific contribution of the screening program to observed declines in mortality rates. Gastric cancer screening is unlikely to be feasible in many Low-Middle Income Countries where the gastric cancer burden is high. Prevention strategies are still under development and the optimal approach may differ depending on local conditions and societal values. The present review gives an overview of the etiology and burden of the disease, and possible prevention strategies for countries and regions confronted with a significant burden of disease. The Korean Society of Gastrointestinal Endoscopy 2014-11 2014-11-30 /pmc/articles/PMC4260094/ /pubmed/25505712 http://dx.doi.org/10.5946/ce.2014.47.6.478 Text en Copyright © 2014 Korean Society of Gastrointestinal Endoscopy http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Focused Review Series: Endoscopic Screening and Surveillance for Gastrointestinal Cancer Park, Jin Young von Karsa, Lawrence Herrero, Rolando Prevention Strategies for Gastric Cancer: A Global Perspective |
title | Prevention Strategies for Gastric Cancer: A Global Perspective |
title_full | Prevention Strategies for Gastric Cancer: A Global Perspective |
title_fullStr | Prevention Strategies for Gastric Cancer: A Global Perspective |
title_full_unstemmed | Prevention Strategies for Gastric Cancer: A Global Perspective |
title_short | Prevention Strategies for Gastric Cancer: A Global Perspective |
title_sort | prevention strategies for gastric cancer: a global perspective |
topic | Focused Review Series: Endoscopic Screening and Surveillance for Gastrointestinal Cancer |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260094/ https://www.ncbi.nlm.nih.gov/pubmed/25505712 http://dx.doi.org/10.5946/ce.2014.47.6.478 |
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