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Differential gene expression in multiple neurological, inflammatory and connective tissue pathways in a spontaneous model of human small vessel stroke

AIMS: Cerebral small vessel disease (SVD) causes a fifth of all strokes plus diffuse brain damage leading to cognitive decline, physical disabilities and dementia. The aetiology and pathogenesis of SVD are unknown, but largely attributed to hypertension or microatheroma. METHODS: We used the spontan...

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Detalles Bibliográficos
Autores principales: Bailey, Emma L, McBride, Martin W, Beattie, Wendy, McClure, John D, Graham, Delyth, Dominiczak, Anna F, Sudlow, Cathie LM, Smith, Colin, Wardlaw, Joanna M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260148/
https://www.ncbi.nlm.nih.gov/pubmed/24417612
http://dx.doi.org/10.1111/nan.12116