Cargando…

Differential gene expression in multiple neurological, inflammatory and connective tissue pathways in a spontaneous model of human small vessel stroke

AIMS: Cerebral small vessel disease (SVD) causes a fifth of all strokes plus diffuse brain damage leading to cognitive decline, physical disabilities and dementia. The aetiology and pathogenesis of SVD are unknown, but largely attributed to hypertension or microatheroma. METHODS: We used the spontan...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bailey, Emma L, McBride, Martin W, Beattie, Wendy, McClure, John D, Graham, Delyth, Dominiczak, Anna F, Sudlow, Cathie LM, Smith, Colin, Wardlaw, Joanna M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260148/ https://www.ncbi.nlm.nih.gov/pubmed/24417612 http://dx.doi.org/10.1111/nan.12116

Ejemplares similares

Effects of dietary salt on gene and protein expression in brain tissue of a model of sporadic small vessel disease
por: Bailey, Emma L., et al.
Publicado: (2018)

Dissecting the genetic components of a quantitative trait locus for blood pressure and renal pathology on rat chromosome 3
por: Koh-Tan, H.H. Caline, et al.
Publicado: (2017)

Genetics of hypertension: From experimental animals to humans
por: Delles, Christian, et al.
Publicado: (2010)

Predictive response-relevant clustering of expression data provides insights into disease processes
por: Hopcroft, Lisa E. M., et al.
Publicado: (2010)

Clinical diagnosis of TIA or minor stroke and prognosis in patients with neurological symptoms: A rapid access clinic cohort
por: Graham, Catriona, et al.
Publicado: (2019)

Enlarged perivascular spaces and cerebral small vessel disease
por: Potter, Gillian M, et al.
Publicado: (2015)

Modeling Superimposed Preeclampsia Using Ang II (Angiotensin II) Infusion in Pregnant Stroke-Prone Spontaneously Hypertensive Rats
por: Morgan, Hannah L., et al.
Publicado: (2018)

Role of Uromodulin in Salt-Sensitive Hypertension
por: Mary, Sheon, et al.
Publicado: (2022)

Genes From a Translational Analysis Support a Multifactorial Nature of White Matter Hyperintensities
por: Lopez, Lorna M., et al.
Publicado: (2015)

Interhemispheric characterization of small vessel disease imaging markers after subcortical infarct
por: Valdés Hernández, Maria del C., et al.
Publicado: (2016)

Lack of Association of White Matter Lesions with Ipsilateral Carotid Artery Stenosis
por: Potter, Gillian M., et al.
Publicado: (2012)

Combined therapeutic benefit of mitochondria-targeted antioxidant, MitoQ(10), and angiotensin receptor blocker, losartan, on cardiovascular function
por: McLachlan, Jennifer, et al.
Publicado: (2014)

Associations of Clinical Stroke Misclassification (‘Clinical-Imaging Dissociation’) in Acute Ischemic Stroke
por: Potter, Gillian, et al.
Publicado: (2010)

From animal models to patients: the role of placental microRNAs, miR-210, miR-126, and miR-148a/152 in preeclampsia
por: Frazier, Sonya, et al.
Publicado: (2020)

Systematic Review of Cerebral Phenotypes Associated With Monogenic Cerebral Small‐Vessel Disease
por: Whittaker, Ed, et al.
Publicado: (2022)

Salt stress in the renal tubules is linked to TAL-specific expression of uromodulin and an upregulation of heat shock genes
por: Graham, Lesley A., et al.
Publicado: (2018)

Gene expression profiling in whole blood of patients with coronary artery disease
por: Taurino, Chiara, et al.
Publicado: (2010)

A comparison of location of acute symptomatic vs. ‘silent’ small vessel lesions
por: Valdés Hernández, Maria del C., et al.
Publicado: (2015)

Intracranial Carotid Calcification on Cranial Computed Tomography: Visual Scoring Methods, Semiautomated Scores, and Volume Measurements in Patients With Stroke
por: Subedi, Deepak, et al.
Publicado: (2015)

Abnormal uterine artery remodelling in the stroke prone spontaneously hypertensive rat
por: Small, Heather Y., et al.
Publicado: (2016)

Inflammatory Markers and Poor Outcome after Stroke: A Prospective Cohort Study and Systematic Review of Interleukin-6
por: Whiteley, William, et al.
Publicado: (2009)

Benchmarking network-based gene prioritization methods for cerebral small vessel disease
por: Zhang, Huayu, et al.
Publicado: (2021)

Microsurgical Salvage of Neonatal Upper Limb Ischaemia Following Intrauterine Brachial Vessel Constriction
por: Clements, Jamie, et al.
Publicado: (2022)

Rare variants of the 3’-5’ DNA exonuclease TREX1 in early onset small vessel stroke
por: McGlasson, Sarah, et al.
Publicado: (2017)

Role of Tumor Necrosis Factor-α and Natural Killer Cells in Uterine Artery Function and Pregnancy Outcome in the Stroke-Prone Spontaneously Hypertensive Rat
por: Small, Heather Yvonne, et al.
Publicado: (2016)

Rationale and Design for the LOnger-term effects of SARS-CoV-2 INfection on blood Vessels And blood pRessure (LOCHINVAR): an observational phenotyping study
por: Lip, Stefanie, et al.
Publicado: (2022)

Tibial Pseudoaneurysm Resulting from Repetitive Blunt Force Athletic Trauma in a Kickbox Athlete
por: McClure, Graham, et al.
Publicado: (2022)

Upregulation of junctional adhesion molecule-A is a putative prognostic marker of hypertension
por: Xu, Haibo, et al.
Publicado: (2012)

Dominance is common in mammals and is associated with trans-acting gene expression and alternative splicing
por: Cui, Leilei, et al.
Publicado: (2023)

Altered Spontaneous Brain Activity Related to Neurologic Dysfunction in Patients With Cerebral Small Vessel Disease
por: Feng, Mengmeng, et al.
Publicado: (2021)

Molecular genetic contributions to self-rated health
por: Harris, Sarah E, et al.
Publicado: (2017)

Differential expression of microRNA-206 and its target genes in preeclampsia
por: Akehurst, Christine, et al.
Publicado: (2015)

Update on cerebral small vessel disease: a dynamic whole-brain disease
por: Shi, Yulu, et al.
Publicado: (2016)

Formal and informal prediction of recurrent stroke and myocardial infarction after stroke: a systematic review and evaluation of clinical prediction models in a new cohort
por: Thompson, Douglas D, et al.
Publicado: (2014)

Modeling connectivity to identify current and future anthropogenic barriers to movement of large carnivores: A case study in the American Southwest
por: McClure, Meredith L., et al.
Publicado: (2017)

Drug prescriptions and dementia incidence: a medication-wide association study of 17000 dementia cases among half a million participants
por: Wilkinson, Tim, et al.
Publicado: (2022)

Neurological Disease in Lupus: Toward a Personalized Medicine Approach
por: McGlasson, Sarah, et al.
Publicado: (2018)

The chemokine receptors ACKR2 and CCR2 reciprocally regulate lymphatic vessel density
por: Lee, Kit M, et al.
Publicado: (2014)

Long-term mortality and recurrent vascular events in lacunar versus non-lacunar ischaemic stroke: A cohort study
por: Portegijs, Suzanne, et al.
Publicado: (2021)

Unravelling the Distinct Effects of Systolic and Diastolic Blood Pressure Using Mendelian Randomisation
por: Le, Nhu Ngoc, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_hu9vlp136tuhc2smamdtdafk1i