A novel serine hydroxymethyltransferase from Arthrobacter nicotianae: characterization and improving catalytic efficiency by rational design

BACKGROUND: Serine hydroxymethyltransferase (SHMT) is the key enzyme in L-serine enzymatic production, suggesting the importance of obtaining a SHMT with high activity. RESULTS: Here, a novel SHMT gene, glyA, was obtained through degenerate oligonucleotide-primed PCR and encoded a novel SHMT with 54...

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Detalles Bibliográficos
Autores principales: Jiang, Wei, Chen, Lin, Hu, Nan, Yuan, Shaohui, Li, Bin, Liu, Ziduo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260256/
https://www.ncbi.nlm.nih.gov/pubmed/25394480
http://dx.doi.org/10.1186/s12896-014-0093-9

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