Extranodal large B-cell type aggressive non-Hodgkin's lymphoma

Non-Hodgkin's lymphomas belong to a group of neoplasm originating from the cells of the lymphoreticular system that show diversity in their manner of presentation, response to therapy and prognosis. Non-Hodgkin's lymphoma accounts for 80–90% of all lymphomas. Although primary intraoral lesions in non-Hodgkin's lymphoma are uncommon, it is important to be aware of them as intraoral manifestations are a presenting symptom in these patients. A 72-year-old Indian male presented with a complaint of asymptomatic swelling in the left side of the face since 1.5 months. A careful clinical evaluation supported by radiologic, histopathologic and immunohistochemical investigations will help in identifying the disease at an early stage, which will result in better prognosis.