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The large conductance Ca(2+) -activated K(+) (BKCa) channel regulates cell proliferation in SH-SY5Y neuroblastoma cells by activating the staurosporine-sensitive protein kinases

Here we investigated on the role of the calcium activated K(+)-channels(BKCa) on the regulation of the neuronal viability. Recordings of the K(+)-channel current were performed using patch-clamp technique in human neuroblastoma cells (SH-SY5Y) in parallel with measurements of the cell viability in t...

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Detalles Bibliográficos
Autores principales: Curci, Angela, Mele, Antonietta, Camerino, Giulia Maria, Dinardo, Maria Maddalena, Tricarico, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260485/
https://www.ncbi.nlm.nih.gov/pubmed/25538629
http://dx.doi.org/10.3389/fphys.2014.00476