Tumor-induced senescent T cells promote the secretion of pro-inflammatory cytokines and angiogenic factors by human monocytes/macrophages through a mechanism that involves Tim-3 and CD40L

Solid tumors are infiltrated by immune cells where macrophages and senescent T cells are highly represented. Within the tumor microenvironment, a cross-talk between the infiltrating cells may occur conditioning the characteristic of the in situ immune response. Our previous work showed that tumors i...

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Detalles Bibliográficos
Autores principales: Ramello, M C, Tosello Boari, J, Canale, F P, Mena, H A, Negrotto, S, Gastman, B, Gruppi, A, Acosta Rodríguez, E V, Montes, C L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260722/
https://www.ncbi.nlm.nih.gov/pubmed/25375372
http://dx.doi.org/10.1038/cddis.2014.451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260722/
https://www.ncbi.nlm.nih.gov/pubmed/25375372
http://dx.doi.org/10.1038/cddis.2014.451

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