Cargando…

Tumor-induced senescent T cells promote the secretion of pro-inflammatory cytokines and angiogenic factors by human monocytes/macrophages through a mechanism that involves Tim-3 and CD40L

Solid tumors are infiltrated by immune cells where macrophages and senescent T cells are highly represented. Within the tumor microenvironment, a cross-talk between the infiltrating cells may occur conditioning the characteristic of the in situ immune response. Our previous work showed that tumors i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ramello, M C, Tosello Boari, J, Canale, F P, Mena, H A, Negrotto, S, Gastman, B, Gruppi, A, Acosta Rodríguez, E V, Montes, C L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260722/ https://www.ncbi.nlm.nih.gov/pubmed/25375372 http://dx.doi.org/10.1038/cddis.2014.451

Ejemplares similares

Unconventional Pro-inflammatory CD4(+) T Cell Response in B Cell-Deficient Mice Infected with Trypanosoma cruzi
por: Gorosito Serrán, Melisa, et al.
Publicado: (2017)

IL-17RA Signaling Reduces Inflammation and Mortality during Trypanosoma cruzi Infection by Recruiting Suppressive IL-10-Producing Neutrophils
por: Tosello Boari, Jimena, et al.
Publicado: (2012)

Polyfunctional KLRG-1(+)CD57(+) Senescent CD4(+) T Cells Infiltrate Tumors and Are Expanded in Peripheral Blood From Breast Cancer Patients
por: Ramello, Maria C., et al.
Publicado: (2021)

The synthetic phospholipid C8-C1P determines pro-angiogenic and pro-reparative features in human macrophages restraining the proinflammatory M1-like phenotype
por: Ortiz Wilczyñski, Juan Manuel, et al.
Publicado: (2023)

CD40 expression by human monocytes: regulation by cytokines and activation of monocytes by the ligand for CD40
Publicado: (1993)

Limited Foxp3(+) Regulatory T Cells Response During Acute Trypanosoma cruzi Infection Is Required to Allow the Emergence of Robust Parasite-Specific CD8(+) T Cell Immunity
por: Araujo Furlan, Cintia L., et al.
Publicado: (2018)

IL-17RA-Signaling Modulates CD8+ T Cell Survival and Exhaustion During Trypanosoma cruzi Infection
por: Tosello Boari, Jimena, et al.
Publicado: (2018)

CD39(+) conventional CD4(+) T cells with exhaustion traits and cytotoxic potential infiltrate tumors and expand upon CTLA-4 blockade
por: Bossio, Sabrina N., et al.
Publicado: (2023)

An optimised protocol for platelet-rich plasma preparation to improve its angiogenic and regenerative properties
por: Etulain, Julia, et al.
Publicado: (2018)

Galectin-3 deficiency drives lupus-like disease by promoting spontaneous germinal centers formation via IFN-γ
por: Beccaria, Cristian Gabriel, et al.
Publicado: (2018)

Decrease of Pro-Angiogenic Monocytes Predicts Clinical Response to Anti-Angiogenic Treatment in Patients with Metastatic Renal Cell Carcinoma
por: Oudard, Stephane, et al.
Publicado: (2021)

Pro-angiogenic cytokines for prediction of outcomes in patients with advanced hepatocellular carcinoma
por: Miyahara, K, et al.
Publicado: (2013)

NLRP3 Blockade Suppresses Pro-Inflammatory and Pro-Angiogenic Cytokine Secretion in Diabetic Retinopathy
por: Chai, Guangrui, et al.
Publicado: (2020)

CD8(+) T Cell Immunity Is Compromised by Anti-CD20 Treatment and Rescued by Interleukin-17A
por: Fiocca Vernengo, Facundo, et al.
Publicado: (2020)

Pro-angiogenic therapeutics for preeclampsia
por: Eddy, Adrian C., et al.
Publicado: (2018)

Maggot Secretions Skew Monocyte-Macrophage Differentiation Away from a Pro-Inflammatory to a Pro-Angiogenic Type
por: van der Plas, Mariena J. A., et al.
Publicado: (2009)

Interleukin-17 signaling influences CD8(+) T cell immunity and tumor progression according to the IL-17 receptor subunit expression pattern in cancer cells
por: Rodriguez, Constanza, et al.
Publicado: (2023)

Downregulation of adaptor protein MyD88 compromises the angiogenic potential of B16 murine melanoma
por: Trucco, Lucas Daniel, et al.
Publicado: (2017)

Senescence-Associated Pro-inflammatory Cytokines and Tumor Cell Plasticity
por: Vernot, Jean Paul
Publicado: (2020)

The pro-inflammatory phenotype of the human non-classical monocyte subset is attributed to senescence
por: Ong, Siew-Min, et al.
Publicado: (2018)

Soluble CD40 Ligand Stimulates the Pro-Angiogenic Function of Peripheral Blood Angiogenic Outgrowth Cells via Increased Release of Matrix Metalloproteinase-9
por: Bou Khzam, Lara, et al.
Publicado: (2013)

Extrafollicular Plasmablasts Present in the Acute Phase of Infections Express High Levels of PD-L1 and Are Able to Limit T Cell Response
por: Serrán, Melisa Gorosito, et al.
Publicado: (2022)

Tim-3 Negatively Regulates IL-12 Expression by Monocytes in HCV Infection
por: Zhang, Ying, et al.
Publicado: (2011)

Tim-3 Coordinates Macrophage-Trophoblast Crosstalk via Angiogenic Growth Factors to Promote Pregnancy Maintenance
por: Cui, Liyuan, et al.
Publicado: (2023)

Sarcoidosis exosomes stimulate monocytes to produce pro-inflammatory cytokines and CCL2
por: Wahlund, Casper J. E., et al.
Publicado: (2020)

NFAM1 Promotes Pro-Inflammatory Cytokine Production in Mouse and Human Monocytes
por: Juchem, Kathryn W., et al.
Publicado: (2022)

Galectin-9 Controls CD40 Signaling through a Tim-3 Independent Mechanism and Redirects the Cytokine Profile of Pathogenic T Cells in Autoimmunity
por: Vaitaitis, Gisela M., et al.
Publicado: (2012)

Bioavailability of Bergamot (Citrus bergamia) Flavanones and Biological Activity of Their Circulating Metabolites in Human Pro-Angiogenic Cells
por: Spigoni, Valentina, et al.
Publicado: (2017)

Arterial Hypertension Is Characterized by Imbalance of Pro-Angiogenic versus Anti-Angiogenic Factors
por: Marek-Trzonkowska, Natalia, et al.
Publicado: (2015)

Abnormal Production of Pro- and Anti-Inflammatory Cytokines by Lupus Monocytes in Response to Apoptotic Cells
por: Sule, Sangeeta, et al.
Publicado: (2011)

Mild dyslipidemia accelerates tumorigenesis through expansion of Ly6C(hi) monocytes and differentiation to pro-angiogenic myeloid cells
por: Tran, Thi, et al.
Publicado: (2022)

Control of the Immune Response by Pro-Angiogenic Factors
por: Voron, Thibault, et al.
Publicado: (2014)

Leptin’s Pro-Angiogenic Signature in Breast Cancer
por: Gonzalez-Perez, Ruben Rene, et al.
Publicado: (2013)

Dectin-1-Mediated Production of Pro-Inflammatory Cytokines Induced by Yeast β-Glucans in Bovine Monocytes
por: Pedro, Ana R. V., et al.
Publicado: (2021)

Mast cell activation is enhanced by Tim1:Tim4 interaction but not by Tim-1 antibodies
por: Phong, Binh, et al.
Publicado: (2016)

Ebola Virus Binding to Tim-1 on T Lymphocytes Induces a Cytokine Storm
por: Younan, Patrick, et al.
Publicado: (2017)

Senescent peritoneal mesothelium induces a pro-angiogenic phenotype in ovarian cancer cells in vitro and in a mouse xenograft model in vivo
por: Mikuła-Pietrasik, Justyna, et al.
Publicado: (2015)

Methylglyoxal Impairs the Pro-Angiogenic Ability of Mouse Adipose-Derived Stem Cells (mADSCs) via a Senescence-Associated Mechanism
por: Leone, Alessia, et al.
Publicado: (2023)

Down-Regulation of Tim-3 in Monocytes and Macrophages in Plasmodium Infection and Its Association with Parasite Clearance
por: Hou, Nan, et al.
Publicado: (2017)

HDL Interfere with the Binding of T Cell Microparticles to Human Monocytes to Inhibit Pro-Inflammatory Cytokine Production
por: Carpintero, Rakel, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_27unpvkulc6bff5k5n57pnvi5j