BIS targeting induces cellular senescence through the regulation of 14-3-3 zeta/STAT3/SKP2/p27 in glioblastoma cells

Cellular senescence is an important mechanism for preventing tumor progression. The elevated expression of Bcl-2-interacting cell death suppressor (BIS), an anti-apoptotic and anti-stress protein, often correlates with poor prognosis in several cancers including glioblastoma; however, the role of BI...

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Detalles Bibliográficos
Autores principales: Lee, J-J, Lee, J-S, Cui, M N, Yun, H H, Kim, H Y, Lee, S H, Lee, J-H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260756/
https://www.ncbi.nlm.nih.gov/pubmed/25412315
http://dx.doi.org/10.1038/cddis.2014.501

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