Centrosome-declustering drugs mediate a two-pronged attack on interphase and mitosis in supercentrosomal cancer cells

Classical anti-mitotic drugs have failed to translate their preclinical efficacy into clinical response in human trials. Their clinical failure has challenged the notion that tumor cells divide frequently at rates comparable to those of cancer cells in vitro and in xenograft models. Given the prepon...

Descripción completa

Detalles Bibliográficos
Autores principales: Pannu, V, Rida, P C G, Celik, B, Turaga, R C, Ogden, A, Cantuaria, G, Gopalakrishnan, J, Aneja, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260758/
https://www.ncbi.nlm.nih.gov/pubmed/25412316
http://dx.doi.org/10.1038/cddis.2014.505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260758/
https://www.ncbi.nlm.nih.gov/pubmed/25412316
http://dx.doi.org/10.1038/cddis.2014.505

Ejemplares similares