Cargando…
ROS inhibit autophagy by downregulating ULK1 mediated by the phosphorylation of p53 in selenite-treated NB4 cells
Reactive oxygen species (ROS) have an important role in regulating various cellular processes. Our previous study confirmed that selenite, an anti-tumour agent, triggered apoptosis through the production of ROS in multiple types of cancer cells. In this study, we discovered that ROS also inhibited p...
Autores principales: | Ci, Y, Shi, K, An, J, Yang, Y, Hui, K, Wu, P, Shi, L, Xu, C |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260759/ https://www.ncbi.nlm.nih.gov/pubmed/25429619 http://dx.doi.org/10.1038/cddis.2014.506 |
Ejemplares similares
-
Survivin-2B promotes autophagy by accumulating IKK alpha in the nucleus of selenite-treated NB4 cells
por: Shi, K, et al.
Publicado: (2014) -
The ROS/JNK/ATF2 pathway mediates selenite-induced leukemia NB4 cell cycle arrest and apoptosis in vitro and in vivo
por: An, J J, et al.
Publicado: (2013) -
Involvement of p38 in signal switching from autophagy to apoptosis via the PERK/eIF2α/ATF4 axis in selenite-treated NB4 cells
por: Jiang, Q, et al.
Publicado: (2014) -
TOPK inhibits autophagy by phosphorylating ULK1 and promotes glioma resistance to TMZ
por: Lu, Hui, et al.
Publicado: (2019) -
GSK3B induces autophagy by phosphorylating ULK1
por: Ryu, Hye Young, et al.
Publicado: (2021)