Ionizing radiations sustain glioblastoma cell dedifferentiation to a stem-like phenotype through survivin: possible involvement in radioresistance

Glioblastomas (GBM) are some bad prognosis brain tumors despite a conventional treatment associating surgical resection and subsequent radio-chemotherapy. Among these heterogeneous tumors, a subpopulation of chemo- and radioresistant GBM stem-like cells appears to be involved in the systematic GBM r...

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Detalles Bibliográficos
Autores principales: Dahan, P, Martinez Gala, J, Delmas, C, Monferran, S, Malric, L, Zentkowski, D, Lubrano, V, Toulas, C, Cohen-Jonathan Moyal, E, Lemarie, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260760/
https://www.ncbi.nlm.nih.gov/pubmed/25429620
http://dx.doi.org/10.1038/cddis.2014.509

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