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Impact of Replacing Smear Microscopy with Xpert MTB/RIF for Diagnosing Tuberculosis in Brazil: A Stepped-Wedge Cluster-Randomized Trial

BACKGROUND: Abundant evidence on Xpert MTB/RIF accuracy for diagnosing tuberculosis (TB) and rifampicin resistance has been produced, yet there are few data on the population benefit of its programmatic use. We assessed whether the implementation of Xpert MTB/RIF in routine conditions would (1) incr...

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Detalles Bibliográficos
Autores principales: Durovni, Betina, Saraceni, Valeria, van den Hof, Susan, Trajman, Anete, Cordeiro-Santos, Marcelo, Cavalcante, Solange, Menezes, Alexandre, Cobelens, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260794/
https://www.ncbi.nlm.nih.gov/pubmed/25490549
http://dx.doi.org/10.1371/journal.pmed.1001766