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Development of a Composite Measure of Product Adherence, Protocol Compliance, and Semen Exposure Using DNA and Protein Biomarkers for Topical HIV Prevention Studies

BACKGROUND: Poor and inconsistent use of study products has hindered clinical HIV prevention studies. It is important to be able to monitor product adherence and protocol compliance in order to determine microbicide efficacy and safety more accurately. Current methods for monitoring adherence are su...

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Detalles Bibliográficos
Autores principales: Jacot, Terry A., Nelson, Ashley, Thurman, Andrea, Kashuba, Angela D. M., Archer, David F., Doncel, Gustavo F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260853/
https://www.ncbi.nlm.nih.gov/pubmed/25489736
http://dx.doi.org/10.1371/journal.pone.0114368