Cargando…
Development of a Composite Measure of Product Adherence, Protocol Compliance, and Semen Exposure Using DNA and Protein Biomarkers for Topical HIV Prevention Studies
BACKGROUND: Poor and inconsistent use of study products has hindered clinical HIV prevention studies. It is important to be able to monitor product adherence and protocol compliance in order to determine microbicide efficacy and safety more accurately. Current methods for monitoring adherence are su...
Autores principales: | Jacot, Terry A., Nelson, Ashley, Thurman, Andrea, Kashuba, Angela D. M., Archer, David F., Doncel, Gustavo F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260853/ https://www.ncbi.nlm.nih.gov/pubmed/25489736 http://dx.doi.org/10.1371/journal.pone.0114368 |
Ejemplares similares
-
Rapid measures of user’s adherence to vaginal drug products using attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) and multivariate discriminant techniques
por: Adedipe, Oluwatosin E., et al.
Publicado: (2018) -
Development and clinical assessment of new objective adherence markers for four microbicide delivery systems used in HIV prevention studies
por: Jacot, Terry A., et al.
Publicado: (2018) -
Vaginal Microbiota and Mucosal Pharmacokinetics of Tenofovir in Healthy Women Using a 90-Day Tenofovir/Levonorgestrel Vaginal Ring
por: Thurman, Andrea R., et al.
Publicado: (2022) -
Differences in Local and Systemic TFV PK Among Premenopausal Versus Postmenopausal Women Exposed to TFV 1% Vaginal Gel
por: Thurman, Andrea Ries, et al.
Publicado: (2018) -
Topical Inserts: A Versatile Delivery Form for HIV Prevention
por: Peet, M. Melissa, et al.
Publicado: (2019)