Proof of principle for epitope-focused vaccine design

Vaccines prevent infectious disease largely by inducing protective neutralizing antibodies against vulnerable epitopes. Multiple major pathogens have resisted traditional vaccine development, although vulnerable epitopes targeted by neutralizing antibodies have been identified for several such cases...

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Detalles Bibliográficos
Autores principales: Correia, Bruno E., Bates, John T., Loomis, Rebecca J., Baneyx, Gretchen, Carrico, Christopher, Jardine, Joseph G., Rupert, Peter, Correnti, Colin, Kalyuzhniy, Oleksandr, Vittal, Vinayak, Connell, Mary J., Stevens, Eric, Schroeter, Alexandria, Chen, Man, MacPherson, Skye, Serra, Andreia M., Adachi, Yumiko, Holmes, Margaret A., Li, Yuxing, Klevit, Rachel E., Graham, Barney S., Wyatt, Richard T., Baker, David, Strong, Roland K., Crowe, James E., Johnson, Philip R., Schief, William R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4260937/
https://www.ncbi.nlm.nih.gov/pubmed/24499818
http://dx.doi.org/10.1038/nature12966

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