NMR approaches in structure-based lead discovery: Recent developments and new frontiers for targeting multi-protein complexes

Nuclear magnetic resonance (NMR) spectroscopy is a pivotal method for structure-based and fragment-based lead discovery because it is one of the most robust techniques to provide information on protein structure, dynamics and interaction at an atomic level in solution. Nowadays, in most ligand scree...

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Detalles Bibliográficos
Autores principales: Dias, David M., Ciulli, Alessio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261069/
https://www.ncbi.nlm.nih.gov/pubmed/25175337
http://dx.doi.org/10.1016/j.pbiomolbio.2014.08.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261069/
https://www.ncbi.nlm.nih.gov/pubmed/25175337
http://dx.doi.org/10.1016/j.pbiomolbio.2014.08.012

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