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NMR approaches in structure-based lead discovery: Recent developments and new frontiers for targeting multi-protein complexes
Nuclear magnetic resonance (NMR) spectroscopy is a pivotal method for structure-based and fragment-based lead discovery because it is one of the most robust techniques to provide information on protein structure, dynamics and interaction at an atomic level in solution. Nowadays, in most ligand scree...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Pergamon Press
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261069/ https://www.ncbi.nlm.nih.gov/pubmed/25175337 http://dx.doi.org/10.1016/j.pbiomolbio.2014.08.012 |