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Vasculotoxic and Proinflammatory Effects of Plasma Heme: Cell Signaling and Cytoprotective Responses

The proinfammatory vasculotoxic effects of intravascular hemolysis are modulated by plasma hemoglobin and heme clearance via the haptoglobin/CD163 system and the hemopexin/CD91 system, respectively, and detoxification through the heme oxygenase/ferritin system. However, sudden or excessive hemolysis...

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Detalles Bibliográficos
Autores principales:	Belcher, John D., Nath, Karl A., Vercellotti, Gregory M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261193/ https://www.ncbi.nlm.nih.gov/pubmed/25506596 http://dx.doi.org/10.1155/2013/831596

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