Vascular channels formed by subpopulations of PECAM1(+) melanoma cells

Targeting the vasculature remains a promising approach for treating solid tumors; however, the mechanisms of tumor neovascularization are diverse and complex. Here we uncover a new subpopulation of melanoma cells that express the vascular cell adhesion molecule PECAM1, but not VEGFR-2, and participa...

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Detalles Bibliográficos
Autores principales: Dunleavey, James M., Xiao, Lin, Thompson, Joshua, Kim, Mi Mi, Shields, Janiel M., Shelton, Sarah E., Irvin, David M., Brings, Victoria E., Ollila, David, Brekken, Rolf A., Dayton, Paul A., Melero-Martin, Juan M., Dudley, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261234/
https://www.ncbi.nlm.nih.gov/pubmed/25335460
http://dx.doi.org/10.1038/ncomms6200

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