(64)Cu-Labeled Somatostatin Analogues Conjugated with Cross-Bridged Phosphonate-Based Chelators via Strain-Promoted Click Chemistry for PET Imaging: In silico through in Vivo Studies

[Image: see text] Somatostatin receptor subtype 2 (sstr2) is a G-protein-coupled receptor (GPCR) that is overexpressed in neuroendocrine tumors. The homology model of sstr2 was built and was used to aid the design of new somatostatin analogues modified with phosphonate-containing cross-bridged chela...

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Detalles Bibliográficos
Autores principales: Cai, Zhengxin, Ouyang, Qin, Zeng, Dexing, Nguyen, Kim N., Modi, Jalpa, Wang, Lirong, White, Alexander G., Rogers, Buck E., Xie, Xiang-Qun, Anderson, Carolyn J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261236/
https://www.ncbi.nlm.nih.gov/pubmed/24983404
http://dx.doi.org/10.1021/jm500416f

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