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Analysis of AKT and ERK1/2 protein kinases in extracellular vesicles isolated from blood of patients with cancer
BACKGROUND: Extracellular vesicles (EVs) are small nanometre-sized vesicles that are circulating in blood. They are released by multiple cells, including tumour cells. We hypothesized that circulating EVs contain protein kinases that may be assessed as biomarkers during treatment with tyrosine kinas...
Autores principales: | van der Mijn, Johannes C., Sol, Nik, Mellema, Wouter, Jimenez, Connie R., Piersma, Sander R., Dekker, Henk, Schutte, Lisette M., Smit, Egbert F., Broxterman, Henk J., Skog, Johan, Tannous, Bakhos A., Wurdinger, Thomas, Verheul, Henk M. W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Co-Action Publishing
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261239/ https://www.ncbi.nlm.nih.gov/pubmed/25491250 http://dx.doi.org/10.3402/jev.v3.25657 |
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