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Increase of nerve growth factor levels in the human herniated intervertebral disc: can annular rupture trigger discogenic back pain?

INTRODUCTION: Nerve growth factor (NGF) has an important role in the generation of discogenic pain. We hypothesized that annular rupture is a trigger for discogenic pain through the action of NGF. In this study, the protein levels of NGF in discs from patients with disc herniation were examined and...

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Detalles Bibliográficos
Autores principales: Aoki, Yasuchika, Nakajima, Arata, Ohtori, Seiji, Takahashi, Hiroshi, Watanabe, Fusako, Sonobe, Masato, Terajima, Fumiaki, Saito, Masahiko, Takahashi, Kazuhisa, Toyone, Tomoaki, Watanabe, Atsuya, Nakajima, Takayuki, Takazawa, Makoto, Nakagawa, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261264/
https://www.ncbi.nlm.nih.gov/pubmed/25069717
http://dx.doi.org/10.1186/ar4674